Definiens Tissue Studio 2.1 Availability Announcement

Dear Valued Customer,

It is our pleasure to bring this new release of Definiens Tissue Studio™ 2.1 to you.

About Definiens Tissue Studio™ 2.1

Definiens Tissue Studio™ 2.1 is a minor feature release. It includes about 25 bugfixes to Definiens Tissue Studio™ 2.0 and is a recommended update for customers using any previous version of Tissue Studio.

Key Features

These are some of the key features of the new version:

  • Fluorescence extensions
    • Support for 10–16 bit data
    • Visualization of colocalization per cell / per nucleus
    • Export of Pearsons/Manders correlation coefficient (Cells, Nuclei)
  • Bright field extensions
    • Intensity-based classifications
      • Option to use optical density instead of IHC marker density
      • Membrane Classification into three intensity classes
      • Marker Area Classification into four intensity classes
    • Breast panel
      • Her-2 scoring (DAKO and ASCO) on a cell-by-cell basis
      • Allred score
  • Additional context features
    • Distance of objects to region border, e.g. ‘Distance of 3+ cells to tumor border’.

Please have a look at the complete list of new features and bug fixes, please have a look at the release notes (attached).

Introductory Webinar

A first introduction into the new functionality will be done in an open webinar on November 17th. Please have a look here for more details (coming soon):

For those of you who can't make it to the webinar, the webinar will be recorded and posted in the Definiens Life TV channel on

Software Downloads

The software is available for download from the Definiens Download Center:

Please send an email to and we will be happy to provide you with a username and password for this release.


Licenses for Definiens Tissue Studio™ 2.0 will continue to work. There is no need for a new license request. If you use the workstation installation, please make sure to activate the software by loading your current license file after installation. It is recommended to uninstall all older versions of the software before installing the new version.

Enjoy using this new version of the software!

Yours sincerely,
Kai Hartmann, Product Manager

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